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Open Access Highly Accessed Review

Traditional Chinese medicine: a promising candidate for the treatment of Alzheimer’s disease

Zhi-Kun Sun1, Hong-Qi Yang1 and Sheng-Di Chen2*

Author Affiliations

1 Department of Neurology, Henan Provincial People’s Hospital, 450003, Zhengzhou, Henan Province, People’s Republic of China

2 Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai JiaoTong University School of Medicine, 200025, Shanghai, People’s Republic of China

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Translational Neurodegeneration 2013, 2:6  doi:10.1186/2047-9158-2-6

Published: 28 February 2013

Abstract

Alzheimer’s disease (AD) is an age-related neurodegenerative disorder, characterized clinically by insidious onset of memory and cognition impairment, emergence of psychiatric symptoms and behavioral disorder, and impairment of activities of daily living (ADL). Traditional Chinese medicine (TCM) is practiced in the Chinese health care system for more than 2,000 years. In recent years, scientists have isolated many novel compounds from herbs, some of which improve dementia with fewer side effects than conventional drugs and are regarded as potential anti-AD drugs. In this review, we summarize the latest research progress on TCM showing their possible role of treatment of AD and other demented diseases and possible pharmacological actions.

Keywords:
Alzheimer’s disease; Chinese traditional medicine; Therapeutic approach