Table 4

Results of striatal volume comparisons
Striatal Regionψ PD (n = 65) Healthy Controls (n = 27) F(1,91) p Effect size
Normalized Caudate 0.416% (0.400 – 0.433) 0.468% (0.443 – 0.493) 11.38 0.001 −0.80
Normalized Putamen 0.422% (0.405 – 0.440) 0.459% (0.432 – 0.442) 5.22 0.03 −0.52
Gender effectsψ Male (n = 67) Female (n = 25) F(1,91) p Effect size
Normalized Caudate 0.423% (0.407 – 0.439) 0.461% (0.435 – 0.487) 6.2 0.02 −0.59
Normalized Putamen 0.425% (0.408 – 0.442) 0.456% (0.429 – 0.483) 3.8 0.05 −0.47
Caudate sub-regionsζ PD (n = 58) Healthy Controls (n = 25) F(1,82) p Effect size
Normalized Head 0.351% (0.338 – 0.363) 0.381% (0.363 – 0.399) 7.4 0.008 −0.66
Normalized Body 0.071% (0.064 – 0.077) 0.078% (0.070 – 0.086) 2.0 0.16 −0.32
Cognitively normal comparison* PD normal cognition (n = 41) Healthy Controls (n = 27) F(1,67) p Effect size
Normalized Caudate 0.424% (0.401 – 0.446) 0.470% (0.442 – 0.497) 6.0 0.02 −0.65
Normalized Putamen 0.429% (0.406 – 0.453) 0.465% (0.437 – 0.494) 3.9 0.05 −0.48

Values are estimated marginal means (95% confidence intervals) calculated from analysis controlling for gender and age.

ψAssumed age of 67 years; ζAssumed age of 66.4 years; *Assumed age of 65.7 years.

Pitcher et al.

Pitcher et al. Translational Neurodegeneration 2012 1:17   doi:10.1186/2047-9158-1-17

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