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RNAi-mediated knock-down of Dab and Numb attenuate Aβ levels via γ-secretase mediated APP processing

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Zhongcong Xie^*, Yuanlin Dong, Uta Maeda, Weiming Xia and Rudolph E Tanzi^*

* Corresponding authors: Zhongcong Xie zxie@partners.org - Rudolph E Tanzi tanzi@helix.mgh.harvard.edu

Translational Neurodegeneration 2012, 1:8 doi:10.1186/2047-9158-1-8

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