Figure 7.

Involvement of PI3K/Akt in the effects of Epo on Abeta _(25-35)-induced cell apoptosis determined by Western blotting analysis. As shown in the graph, We treated the cells with PI3K inhibitor LY294002 and found the protective effects of Epo on Abeta_(25-35)-induced cell apoptosis were diminished (P < 0.05) (A-C). Three independent experiments were performed in duplicate (*: P < 0.05 vs. the controls and #: P < 0.05 vs. 20 μM Abeta_(25-35))